Hotel Transylvania: Transformania (also known as Hotel Transylvania 4) is a 2022 American computer-animated adventure comedy film produced by Sony Pictures Animation and released by Amazon Studios. The fourth and final installment of the Hotel Transylvania franchise and the sequel to Hotel Transylvania 3: Summer Vacation (2018), the film is directed by Jennifer Kluska and Derek Drymon (in their respective feature-length directorial debuts) from a screenplay by Amos Vernon, Nunzio Randazzo, and Genndy Tartakovsky (who directed the prior three films). It stars the voices of Andy Samberg, Selena Gomez (who also served as an executive producer alongside Tartakovsky), Kathryn Hahn, Jim Gaffigan, Steve Buscemi, Molly Shannon, David Spade, Keegan-Michael Key, Brian Hull, Fran Drescher, Brad Abrell, and Asher Blinkoff. In this film, Dracula and Johnny, who transformed into a human and monster, must find the way to South America to revert back, before their transformations become permanent.
During the celebration of the 125th anniversary of Hotel Transylvania, Mavis overhears Dracula's plans to retire and leave the hotel to Johnny and her. She tells Johnny who excitedly tells Dracula his plans to renovate the hotel. Worried about Johnny ruining the hotel, Dracula lies to him saying that there is a real-estate law which only lets monsters own the hotel, disappointing Johnny.
Van Helsing decides to help Johnny using a ray that turns people into monsters and vice-versa; after testing it on his guinea pig Gigi, he uses it on Johnny who turns into a dragon-like monster. Learning about monster Johnny, Dracula tries to turn him back to normal but accidentally turns himself into a human and breaks the ray's crystal. Van Helsing tells Dracula and Johnny that they can still turn themselves back to normal by getting a new crystal which lies in a cave in South America, so Dracula and Johnny set off to do so.
Dracula's friends Frank, Wayne, Griffin and Murray end up becoming humans as well as a result of drinking from a fountain that was contaminated by the ray during Dracula chasing Johnny earlier. Mavis and Ericka confront Van Helsing after learning about Dracula and Johnny's whereabouts in the news, but he warns them about the effects of the ray, as people who become monsters become more hostile later. With this in mind, the rest of the gang head to South America to find Dracula and Johnny.
While traveling through the South American jungle, Dracula and Johnny begin to bond and just as Dracula is about to confess that he lied about the monster real-estate law, the rest of the group finds them. Things turn sour when Dracula admits his deception regarding passing over the hotel to Mavis and Johnny. This prompts an upset Johnny to believe Dracula does not consider him family and runs away.
Mavis goes to find Johnny while Dracula and the rest of the gang go to find the crystal. Mavis finds Johnny, but the transformation has turned him very volatile. She leads him to the cave where they finally find the crystal. When Mavis tries to turn Johnny back to normal, nothing happens. In desperation, Dracula lets himself get captured by Johnny and goes on a remorseful tangent about how wrong he was about Johnny and how he should see the best in him. This brings Johnny back to his senses, and he is returned to normal.
With Dracula and his friends turned back to normal, they return home only to find the hotel has been destroyed by Gigi. After turning Gigi back to normal, Dracula bemoans his loss. He soon decides to let Mavis and Johnny rebuild to their liking.
A year later, Mavis and Johnny make Dracula see the re-built Hotel Transylvania.